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Coronavirus research updates: A finely detailed map reveals a viral protein’s Achilles’ heel

Volunteer Melissa Harting of Harpursville, New York, receives an injection as part of a COVID-19 vaccine trial. Credit: Hans Pennink/AP/Shutterstock
Volunteer Melissa Harting of Harpursville, New York, receives an injection as part of a COVID-19 vaccine trial. Credit: Hans Pennink/AP/Shutterstock
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Excerpt: An experimental coronavirus vaccine seems to have completely prevented infection in most monkeys that received the jab.

Nature, Published online: 24 June 2020; doi:10.1038/d41586-020-00502-w

30 July — Vaccine candidate protects monkeys from infection

An experimental coronavirus vaccine seems to have completely prevented infection in most monkeys that received the jab.

Hanneke Schuitemaker at Janssen Vaccines and Prevention in Leiden, the Netherlands, Dan Barouch at Beth Israel Deaconess Medical Center in Boston, Massachusetts, and their colleagues gave 32 rhesus macaques (Macaca mulatta) a single dose of one of 7 vaccines (N. B. Mercado et alNature http://doi.org/d5d4; 2020). Each vaccine comprised a weakened respiratory virus coding for one of seven forms of SARS-CoV-2’s spike protein.

After vaccination, nearly all the monkeys made neutralizing antibodies — powerful immune molecules that can block infection — and T cells that trigger other immune responses. When monkeys were exposed to SARS-CoV-2, the most potent of the vaccines prevented lung infection in six out of six animals that received it, and nasal infection in five out of six.

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chroniclesofcarlos

chroniclesofcarlos

Are Bigfoot real? Yes, they are! I investigate, create, and share mainstream educational content, Bigfoot and related phenomena, and the scientific methods and principles that corroborate our stories. I have lived and traveled all over North America, Europe, and Africa, have had encounters with Bigfoot and UFOs in North America, and have even had an NDE in Africa. Education: BA and MA in Biological Anthropology Languages: English and Spanish Career: Certified Coach and Teacher, Licensed Entrepreneur Passions: coaching, mentoring, learning, teaching, coaching; the sciences, and cryptozoology Subjects: The Sciences, Cryptozoology

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Are Bigfoot real? Yes, they are!

I investigate, create, and share mainstream educational content, Bigfoot encounters and other mysteries, mythologies, and legends of the unknown, and the scientific methods and principles that corroborate our stories.

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